Prevalence of exclusive breastfeeding and its determinants in first 6 months of life: A prospective study

Background: Exclusive breastfeeding for first 6 months of life is recommended under Infant and Young Child Feeding practices in India. The objective of present study was to estimate the prevalence of exclusive breastfeeding during first 6 months of life of babies and to identify factors that interfere with the practice in the study area. Methods: A prospective cohort of 462 women who delivered at maternity unit of Government Medical College & Hospital, Rajkot, which is a tertiary care centre for the district, was studied. Data collection was done at hospital as well as during home visits of babies at 1, 3 and 6 months. Factors related to cessation of breastfeeding were analyzed using univariate, bivariate and multivariate analysis. Results: All 462 mothers reported breastfeeding their newborns. Prevalence of exclusive breastfeeding reported at 3 months was 97% which declined to 62% by 6 months of age of infants. Bivariate analysis revealed no significant association between interruption of exclusive breastfeeding before 6 months of age and various demographic, socioeconomic, maternal and infant characteristics. Multivariate analysis by logistic regression demonstrated no association between discontinuation of exclusive breastfeeding and socioeconomic status, maternal education and maternal age, number of antenatal visits, maternal employment and initiation of breastfeeding after delivery. Conclusion: Exclusive breastfeeding prevalence rate found higher than at national level indicating better feeding practices in these part of India. Also, factors classically considered as supportive for breastfeeding had shown no association with breastfeeding pattern in present study

CO2 Emissions reduction strategies and economic development of India

This paper examines the consequences of alternative CO2 emission reduction strategies on economic development and, in particular, the implications for the poor by empirically implementing an economy-wide model for India over a 35-year time horizon. A multi-sectoral, inter-temporal model in the activity analysis framework is used for this purpose. The model with specific technological alternatives, endogenous income distribution, truly dynamic behaviour and covering the whole economy is an integrated top-down bottom-up model. The results show that CO2 emission reduction imposes costs in terms of lower GDP and higher poverty. Cumulative emission reduction targets are, however, preferable to annual reduction targets and that a dynamically optimum strategy can help reduce the burden of emission reductions. The scenarios involving compensation for the loss in welfare are not very encouraging as they require large capital inflows. Contrasted with these, scenarios involving tradable emission quota give India an incentive to be carbon efficient. It becomes a net seller for the first 25 years and because of reduction in carbon intensity it would demand less in later years when it becomes a net buyer. The results suggest that for India, and other developing countries, the window of opportunity to sell carbon quotas is the next two decades or so.

Further constraints on neutron star crustal properties in the low-mass X-ray binary 1RXS J180408.9−-342058

We report on two new quiescent {\it XMM-Newton} observations (in addition to the earlier {\it Swift}/XRT and {\it XMM-Newton} coverage) of the cooling neutron star crust in the low-mass X-ray binary 1RXS J180408.9$-$342058. Its crust was heated during the $\sim$4.5 month accretion outburst of the source. From our quiescent observations, fitting the spectra with a neutron star atmosphere model, we found that the crust had cooled from $\sim$ 100 eV to $\sim$73 eV from $\sim$8 days to $\sim$479 days after the end of its outburst. However, during the most recent observation, taken $\sim$860 days after the end of the outburst, we found that the crust appeared not to have cooled further. This suggested that the crust had returned to thermal equilibrium with the neutron star core. We model the quiescent thermal evolution with the theoretical crustal cooling code NSCool and find that the source requires a shallow heat source, in addition to the standard deep crustal heating processes, contributing $\sim$0.9 MeV per accreted nucleon during outburst to explain its observed temperature decay. Our high quality {\it XMM-Newton} data required an additional hard component to adequately fit the spectra. This slightly complicates our interpretation of the quiescent data of 1RXS J180408.9$-$342058. The origin of this component is not fully understood.Comment: Accepted for publication by MNRA

Osmotic Gradients Induce Bio-Reminiscent Morphological Transformations in Giant Unilamellar Vesicles

We report observations of large-scale, in-plane and out-of-plane membrane deformations in giant uni- and multilamellar vesicles composed of binary and ternary lipid mixtures in the presence of net transvesicular osmotic gradients. The lipid mixtures we examined consisted of binary mixtures of DOPC and DPPC lipids and ternary mixtures comprising POPC, sphingomyelin and cholesterol over a range of compositions – both of which produce co-existing phases for selected ranges of compositions at room temperature under thermodynamic equilibrium. In the presence of net osmotic gradients, we find that the in-plane phase separation potential of these mixtures is non-trivially altered and a variety of out-of-plane morphological remodeling events occur. The repertoire of membrane deformations we observe display striking resemblance to their biological counterparts in live cells encompassing vesiculation, membrane fission and fusion, tubulation and pearling, as well as expulsion of entrapped vesicles from multicompartmental giant unilamellar vesicles through large, self-healing transient pores. These observations suggest that the forces introduced by simple osmotic gradients across membrane boundaries could act as a trigger for shape-dependent membrane and vesicle trafficking activities. We speculate that such coupling of osmotic gradients with membrane properties might have provided lipid-mediated mechanisms to compensate for osmotic stress during the early evolution of membrane compartmentalization in the absence of osmoregulatory protein machinery